Since I love reading so much...
Found at Booking It Through Thursday
Who’s the worst fictional villain you can think of? As in, the one you hate the most, find the most evil, are happiest to see defeated? Not the cardboard, two-dimensional variety, but the most deliciously-written, most entertaining, best villain? Not necessarily the most “evil,” so much as the best-conceived on the part of the author…oh, you know what I mean!
The only "villain" I can think of at the moment is Crake from Atwood's Oryx and Crake. While its debatable if he intended to be villainous or merely was doing what he thought was beneficial to humanity I think he intended to cause harm to some extent. He is in no way 2 dimensional, especially as you learn more about his childhood. Crake brings up the age old "nature vs nurture" arguement as we wonder whether he is truly evil or if his upbringing causes his actions .